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KMID : 0358420100530100888
Korean Journal of Obstetrics and Gynecology
2010 Volume.53 No. 10 p.888 ~ p.893
The efficacy of a real-time optoelectronic device as a diagnostic tool of over cervical intraepithelial neoplasia 1 lesion
Lim Hyung-Su

Kim Min-Jeong
Park Kyung-Eui
Chung Hyun-Hoon
Park Noh-Hyun
Song Yong-Sang
Kang Soon-Beom
Abstract
Objective: The purpose of this study was to evaluate the sensitivity, specificity and accuracy of a real-time optoelectronic device (TruScreen) as a diagnostic tool of cervical intraepithelial neoplasia (CIN) or cervical cancer.

Methods: Two hundred ninety two patients who had been presented with previously abnormal Papanicolaou (Pap) smear or abnormal colposcopic findings between February 2009 and September 2009 were analyzed. The sensitivities, specificities and accuracies of TruScreen and liquid-based cytology were evaluated.

Results: As a diagnostic tool of CIN, carcinoma in situ (CIS), and cervical cancer, TruScreen appeared sensitive enough compared with liquid-based cytology (82.8% vs 75.9%), but the difference is statistically not significant (P=0.687). Specificity and accuracy of TruScreen were similar to those of liquid-based cytology (specificity 81.4% vs 83.3%, accuracy 81.5% vs 82.5%).

Conclusion: The present study suggests that the TruScreen could be an option as a tool of screening test in CIN, CIS, and cervical cancer and also be used combined with Pap smear.
KEYWORD
Cervical intraepithelial neoplasia, Cervical cancer, TruScreen, Liquid-based cytology
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